GRAEFE'S SYMPTOM

\ɡɹˈiːfs sˈɪmptəm], \ɡɹˈiːfs sˈɪmptəm], \ɡ_ɹ_ˈiː_f_s s_ˈɪ_m_p_t_ə_m]\

Definitions of GRAEFE'S SYMPTOM

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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