A272
\ˌe͡ɪ tˈuːhˈʌndɹədən sˈɛvəntitˈuː], \ˌeɪ tˈuːhˈʌndɹədən sˈɛvəntitˈuː], \ˌeɪ t_ˈuː_h_ˈʌ_n_d_ɹ_ə_d_ə_n s_ˈɛ_v_ə_n_t_i_t_ˈuː]\
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A macrolide antibiotic of the oligomycin group, obtained from Streptomyces rutgersensis. It is used in cytochemistry as a tool to inhibit various ATPases and to uncouple oxidative phosphorylation from electron transport and also clinically as an antifungal agent.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.