A20 HANDLER

\ˌe͡ɪ twˈɛnti hˈandlə], \ˌe‍ɪ twˈɛnti hˈandlə], \ˌeɪ t_w_ˈɛ_n_t_i h_ˈa_n_d_l_ə]\
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1985 - The Free On-line Dictionary of Computing
By Denis Howe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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