SJOGREN SYNDROME
\ˈɛsd͡ʒˈɒɡɹən sˈɪndɹə͡ʊm], \ˈɛsdʒˈɒɡɹən sˈɪndɹəʊm], \ˈɛ_s_dʒ_ˈɒ_ɡ_ɹ_ə_n s_ˈɪ_n_d_ɹ_əʊ_m]\
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Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.