RAMON DE LA CRUZ

\ɹɐmˈə͡ʊn də lˌa kɹˈuːz], \ɹɐmˈə‍ʊn də lˌa kɹˈuːz], \ɹ_ɐ_m_ˈəʊ_n d_ə l_ˌa k_ɹ_ˈuː_z]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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