KININOGEN CYSTATINS
\kˈɪnɪnəd͡ʒən sˈɪstɐtˌɪnz], \kˈɪnɪnədʒən sˈɪstɐtˌɪnz], \k_ˈɪ_n_ɪ_n_ə_dʒ_ə_n s_ˈɪ_s_t_ɐ_t_ˌɪ_n_z]\
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Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.