CHITOBIASE
\t͡ʃɪtˈə͡ʊbɪˌe͡ɪs], \tʃɪtˈəʊbɪˌeɪs], \tʃ_ɪ_t_ˈəʊ_b_ɪ__ˌeɪ_s]\
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2-Acetamido-2-deoxy-beta-D-glucoside acetamidodeoxygluco-hydrolase. Catalyzes the hydrolysis of terminal, non-reducing 2-acetamido-2-deoxy-beta-glucose residues in chitobiose and higher analogs as well as in glycoproteins. Has been used widely in structural studies on bacterial cell walls and in the study of diseases such as mucolipidosis and various inflammatory disorders of muscle and connective tissue.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.