CALCITRIOL RECEPTOR
\kˈalsɪtɹɪˌɒl ɹɪsˈɛptə], \kˈalsɪtɹɪˌɒl ɹɪsˈɛptə], \k_ˈa_l_s_ɪ_t_ɹ_ɪ__ˌɒ_l ɹ_ɪ_s_ˈɛ_p_t_ə]\
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Proteins, usually found in the cytoplasm, that specifically bind calcitriol, migrate to the nucleus, and regulate transcription of specific segments of DNA. Vitamin D is converted in the liver and kidney to calcitriol and ultimately acts through these receptors.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.