SLUDGE-HOLE
\slˈʌd͡ʒhˈə͡ʊl], \slˈʌdʒhˈəʊl], \s_l_ˈʌ_dʒ_h_ˈəʊ_l]\
Definitions of SLUDGE-HOLE
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.