SLUDER'S METHOD OR OPERATION

\slˈuːdəz mˈɛθəd ɔːɹ ˌɒpəɹˈe͡ɪʃən], \slˈuːdəz mˈɛθəd ɔːɹ ˌɒpəɹˈe‍ɪʃən], \s_l_ˈuː_d_ə_z m_ˈɛ_θ_ə_d__ ɔː_ɹ ˌɒ_p_ə_ɹ_ˈeɪ_ʃ_ə_n]\

Definitions of SLUDER'S METHOD OR OPERATION

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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