VALLEY OF CEREBELLUM
\vˈalɪ ɒv sˌɛɹɪbˈɛləm], \vˈalɪ ɒv sˌɛɹɪbˈɛləm], \v_ˈa_l_ɪ_ ɒ_v s_ˌɛ_ɹ_ɪ_b_ˈɛ_l_ə_m]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.