TRANSIENT CEREBRAL ISCHEMIA
\tɹˈansi͡ənt səɹˈiːbɹə͡l ɪskˈiːmi͡ə], \tɹˈansiənt səɹˈiːbɹəl ɪskˈiːmiə], \t_ɹ_ˈa_n_s_iə_n_t s_ə_ɹ_ˈiː_b_ɹ_əl ɪ_s_k_ˈiː_m_iə]\
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Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.