TOTI'S OPERATION

\tˈə͡ʊtiz ˌɒpəɹˈe͡ɪʃən], \tˈə‍ʊtiz ˌɒpəɹˈe‍ɪʃən], \t_ˈəʊ_t_i_z ˌɒ_p_ə_ɹ_ˈeɪ_ʃ_ə_n]\

Definitions of TOTI'S OPERATION

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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