SPECIFIC CAUSE

\spəsˈɪfɪk kˈɔːz], \spəsˈɪfɪk kˈɔːz], \s_p_ə_s_ˈɪ_f_ɪ_k k_ˈɔː_z]\

Definitions of SPECIFIC CAUSE

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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