RETROGRADE AMNESIAS
\ɹˌɛtɹə͡ʊɡɹˈe͡ɪd amnˈiːzi͡əz], \ɹˌɛtɹəʊɡɹˈeɪd amnˈiːziəz], \ɹ_ˌɛ_t_ɹ_əʊ_ɡ_ɹ_ˈeɪ_d a_m_n_ˈiː_z_iə_z]\
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Loss of the ability to recall information that had been previously encoded in memory prior to a specified or approximate point in time. This process may be organic or psychogenic in origin. Organic forms may be associated with CRANIOCEREBRAL TRAUMA; CEREBROVASCULAR ACCIDENTS; SEIZURES; DEMENTIA; and a wide variety of other conditions that impair cerebral function. (From Adams et al., Principles of Neurology, 6th ed, pp426-9)
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.