PROTO ONCOGENE PROTEINS C ABL
\pɹˈə͡ʊtə͡ʊ ˈɒnkə͡ʊd͡ʒˌiːn pɹˈə͡ʊtiːnz sˈiː ˈabə͡l], \pɹˈəʊtəʊ ˈɒnkəʊdʒˌiːn pɹˈəʊtiːnz sˈiː ˈabəl], \p_ɹ_ˈəʊ_t_əʊ ˈɒ_n_k_əʊ_dʒ_ˌiː_n p_ɹ_ˈəʊ_t_iː_n_z s_ˈiː_ ˈa_b_əl]\
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Non-receptor tyrosine kinases encoded by the c-abl gene. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal hematopoiesis especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.
By DataStellar Co., Ltd
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Nearby Words
- proto oncogene protein sis
- proto oncogene protein src
- proto oncogene protein trk
- proto oncogene proteins
- proto oncogene proteins abl
- Proto Oncogene Proteins c abl
- proto oncogene proteins c bcl 1
- proto oncogene proteins c bcl 2
- proto oncogene proteins c erba
- proto oncogene proteins c erbb 2
- proto oncogene proteins c fos