PRIMA DONNA
\pɹˈiːmə dˈɒnə], \pɹˈiːmə dˈɒnə], \p_ɹ_ˈiː_m_ə d_ˈɒ_n_ə]\
Definitions of PRIMA DONNA
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.