PLUMBAGINE
\plˈʌmbɐd͡ʒˌɪn], \plˈʌmbɐdʒˌɪn], \p_l_ˈʌ_m_b_ɐ_dʒ_ˌɪ_n]\
Definitions of PLUMBAGINE
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.