PLIMMER’S BODIES

\plˈɪməz bˈɒdɪz], \plˈɪməz bˈɒdɪz], \p_l_ˈɪ_m_ə_z b_ˈɒ_d_ɪ_z]\

Definitions of PLIMMER’S BODIES

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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