PLEA BARGAINING
\plˈiː bˈɑːɡɪnɪŋ], \plˈiː bˈɑːɡɪnɪŋ], \p_l_ˈiː b_ˈɑː_ɡ_ɪ_n_ɪ_ŋ]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.