PLAYFAIR’S METHOD

\plˈe͡ɪfe͡əz mˈɛθəd], \plˈe‍ɪfe‍əz mˈɛθəd], \p_l_ˈeɪ_f_eə_z m_ˈɛ_θ_ə_d]\

Definitions of PLAYFAIR’S METHOD

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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