PHILIP DODDRIDGE

\fˈɪlɪp dˈɒdɹɪd͡ʒ], \fˈɪlɪp dˈɒdɹɪd‍ʒ], \f_ˈɪ_l_ɪ_p d_ˈɒ_d_ɹ_ɪ_dʒ]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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