PASTIA'S SIGN

\pˈast͡ʃəz sˈa͡ɪn], \pˈast‍ʃəz sˈa‍ɪn], \p_ˈa_s_tʃ_ə_z s_ˈaɪ_n]\

Definitions of PASTIA'S SIGN

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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