OPIUM DENARCOTINATUM

\ˈə͡ʊpi͡əm dˌɛnɑːkˌɒtɪnˈɑːtəm], \ˈə‍ʊpi‍əm dˌɛnɑːkˌɒtɪnˈɑːtəm], \ˈəʊ_p_iə_m d_ˌɛ_n_ɑː_k_ˌɒ_t_ɪ_n_ˈɑː_t_ə_m]\

Definitions of OPIUM DENARCOTINATUM

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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