OBTURATORS

\ɒbt͡ʃəɹˈe͡ɪtəz], \ɒbt‍ʃəɹˈe‍ɪtəz], \ɒ_b_tʃ_ə_ɹ_ˈeɪ_t_ə_z]\

Definitions of OBTURATORS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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