NARCOLEPTIC SYNDROMES
\nˌɑːkə͡ʊlˈɛptɪk sˈɪndɹə͡ʊmz], \nˌɑːkəʊlˈɛptɪk sˈɪndɹəʊmz], \n_ˌɑː_k_əʊ_l_ˈɛ_p_t_ɪ_k s_ˈɪ_n_d_ɹ_əʊ_m_z]\
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A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50 (2 Suppl 1):S2-S7)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.