KAOLIN CEPHALIN COAGULATION TIME
\kˈe͡ɪəlˌɪn sˈɛfɐlˌɪn kə͡ʊˌaɡjʊlˈe͡ɪʃən tˈa͡ɪm], \kˈeɪəlˌɪn sˈɛfɐlˌɪn kəʊˌaɡjʊlˈeɪʃən tˈaɪm], \k_ˈeɪ_ə_l_ˌɪ_n s_ˈɛ_f_ɐ_l_ˌɪ_n k_əʊ_ˌa_ɡ_j_ʊ_l_ˈeɪ_ʃ_ə_n t_ˈaɪ_m]\
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Test of the intrinsic (factors VIII, IX, XI, and XII) and common (fibrinogen, prothrombin, factors V and X) pathways of coagulation in which a mixture of plasma and phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides) is recalcified and the time required for the appearance of fibrin strands measured. Activation may be provided by contact with the glass tube or exposure to activators (e.g., ellagic acid, particulate silicates such as diatomaceous earth or kaolin) before addition of the calcium chloride. It is used as a screening test and to monitor heparin therapy.
By DataStellar Co., Ltd