JONNESCO'S FOSSA'S METHOD

\d͡ʒənˈɛskə͡ʊz fˈɒsəz mˈɛθəd], \d‍ʒənˈɛskə‍ʊz fˈɒsəz mˈɛθəd], \dʒ_ə_n_ˈɛ_s_k_əʊ_z f_ˈɒ_s_ə_z m_ˈɛ_θ_ə_d]\

Definitions of JONNESCO'S FOSSA'S METHOD

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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