INTEGRIN BETA2
\ɪntˈɛɡɹɪn bˈiːtə tˈuː], \ɪntˈɛɡɹɪn bˈiːtə tˈuː], \ɪ_n_t_ˈɛ_ɡ_ɹ_ɪ_n b_ˈiː_t_ə t_ˈuː]\
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Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE-ADHESION). A defect in the gene encoding CD18 causes LEUKOCYTE-ADHESION DEFICIENCY SYNDROME.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.