FATAL DEFECT

\fˈe͡ɪtə͡l dˈiːfɛkt], \fˈe‍ɪtə‍l dˈiːfɛkt], \f_ˈeɪ_t_əl d_ˈiː_f_ɛ_k_t]\

Definitions of FATAL DEFECT

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1910 - Black's Law Dictionary (2nd edition)
By Henry Campbell Black

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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