ENDOUTERITIS
\ˌɛndə͡ʊjˌuːtəɹˈa͡ɪtɪs], \ˌɛndəʊjˌuːtəɹˈaɪtɪs], \ˌɛ_n_d_əʊ_j_ˌuː_t_ə_ɹ_ˈaɪ_t_ɪ_s]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.