DOTHIENTERITIS

\dˌɒθi͡əntəɹˈa͡ɪtɪs], \dˌɒθi‍əntəɹˈa‍ɪtɪs], \d_ˌɒ_θ_iə_n_t_ə_ɹ_ˈaɪ_t_ɪ_s]\
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1898 - Warner's pocket medical dictionary of today.
By William R. Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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