DIES CANICULARES

\dˈa͡ɪz kanˈɪkjʊlˌe͡əz], \dˈa‍ɪz kanˈɪkjʊlˌe‍əz], \d_ˈaɪ_z k_a_n_ˈɪ_k_j_ʊ_l_ˌeə_z]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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