CZAPLEWSKI'S BACILLUS

\sˈiːzaplˈuːskɪz bˈasɪləs], \sˈiːzaplˈuːskɪz bˈasɪləs], \s_ˈiː_z_a_p_l_ˈuː_s_k_ɪ_z b_ˈa_s_ɪ_l_ə_s]\

Definitions of CZAPLEWSKI'S BACILLUS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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