COFFIN NAIL

\kˈɒfɪn nˈe͡ɪl], \kˈɒfɪn nˈe‍ɪl], \k_ˈɒ_f_ɪ_n n_ˈeɪ_l]\
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2006 - WordNet 3.0
By Princeton University
 
2011 - English Dictionary Database
By DataStellar Co., Ltd

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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