CHROMOPHIL SUBSTANCE

\kɹˈə͡ʊməfˌɪl sˈʌbstəns], \kɹˈə‍ʊməfˌɪl sˈʌbstəns], \k_ɹ_ˈəʊ_m_ə_f_ˌɪ_l s_ˈʌ_b_s_t_ə_n_s]\

Definitions of CHROMOPHIL SUBSTANCE

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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