CALCOSPHERITE

\kˈalkəsfəɹˌa͡ɪt], \kˈalkəsfəɹˌa‍ɪt], \k_ˈa_l_k_ə_s_f_ə_ɹ_ˌaɪ_t]\

Definitions of CALCOSPHERITE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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