BLOCKING ANTIBODIES
\blˈɒkɪŋ ˈantɪbˌɒdɪz], \blˈɒkɪŋ ˈantɪbˌɒdɪz], \b_l_ˈɒ_k_ɪ_ŋ ˈa_n_t_ɪ_b_ˌɒ_d_ɪ_z]\
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Antibodies that inhibit the reaction between antigen and other antibodies or sensitized T-lymphocytes (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IgE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by cytotoxic T-lymphocytes have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.