ABEL-SHITTIM

\ˈe͡ɪbə͡lʃˈɪtɪm], \ˈe‍ɪbə‍lʃˈɪtɪm], \ˈeɪ_b_əl_ʃ_ˈɪ_t_ɪ_m]\

Definitions of ABEL-SHITTIM

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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