15 HYDROXY 11 ALPHA,9 ALPHA (EPOXYMETHANO)PROSTA 5,13 DIENOIC ACID
\fˈɪftiːn hˈa͡ɪdɹɒksi ɪlˈɛvən ˈalfə nˈa͡ɪn ˈalfə ɪpˌɒksa͡ɪmθˈɑːnə͡ʊ pɹˈɒstə fˈa͡ɪv θˈɜːtiːn dˈi͡ənə͡ʊɪk ˈasɪd], \fˈɪftiːn hˈaɪdɹɒksi ɪlˈɛvən ˈalfə nˈaɪn ˈalfə ɪpˌɒksaɪmθˈɑːnəʊ pɹˈɒstə fˈaɪv θˈɜːtiːn dˈiənəʊɪk ˈasɪd], \f_ˈɪ_f_t_iː_n h_ˈaɪ_d_ɹ_ɒ_k_s_i_ ɪ_l_ˈɛ_v_ə_n ˈa_l_f_ə n_ˈaɪ_n ˈa_l_f_ə__ ɪ_p_ˌɒ_k_s_aɪ_m_θ_ˈɑː_n_əʊ__ p_ɹ_ˈɒ_s_t_ə f_ˈaɪ_v θ_ˈɜː_t_iː_n d_ˈiə_n_əʊ_ɪ_k ˈa_s_ɪ_d]\
Definitions of 15 HYDROXY 11 ALPHA,9 ALPHA (EPOXYMETHANO)PROSTA 5,13 DIENOIC ACID
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A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of vasopressin and activation of phospholipase C. (From J Pharmacol Exp Ther 1983;224 (1): 108-117; Biochem J 1984;222 (1):103-110)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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