WELLS'S FACIES

\wˈɛlzɪz fˈe͡ɪsɪz], \wˈɛlzɪz fˈe‍ɪsɪz], \w_ˈɛ_l_z_ɪ_z f_ˈeɪ_s_ɪ_z]\

Definitions of WELLS'S FACIES

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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