VNTR REGIONS
\vˌiːˌɛntˌiːˈɑː ɹˈiːd͡ʒənz], \vˌiːˌɛntˌiːˈɑː ɹˈiːdʒənz], \v_ˌiː__ˌɛ_n_t_ˌiː__ˈɑː ɹ_ˈiː_dʒ_ə_n_z]\
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Tandem arrays of moderately repetitive (5-50 repeats) short (10-60 bases) DNA sequences found dispersed throughout the genome and clustered near telomeres. Their degree of repetition is two to several hundred at each locus. Loci number in the thousands but each locus shows a distinctive repeat unit. Minisatellite repeats are often called variable number of tandem repeats.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.