VIRUS ACTIVATION
\vˈa͡ɪɹəs ˌaktɪvˈe͡ɪʃən], \vˈaɪɹəs ˌaktɪvˈeɪʃən], \v_ˈaɪ_ɹ_ə_s ˌa_k_t_ɪ_v_ˈeɪ_ʃ_ə_n]\
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The mechanism by which latent viruses, such as genetically transmitted tumor viruses or prophages of lysogenic bacteria, are induced to replicate and are released as infectious viruses. It may be effected by various endogenous and exogenous stimuli, including B-cell lipopolysaccharides, glucocorticoid hormones, halogenated pyrimidines, ionizing radiation, ultraviolet light, and superinfecting viruses.
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.