SCRAPIE PRP
\skɹˈapa͡ɪ pˌiːˈɑː pˈiː], \skɹˈapaɪ pˌiːˈɑː pˈiː], \s_k_ɹ_ˈa_p_aɪ p_ˌiː__ˈɑː p_ˈiː]\
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Abnormal isoform of prion proteins (PRIONS) resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES).
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.