SCHISTORRHACIS
\ʃˈɪstəɹˌasɪs], \ʃˈɪstəɹˌasɪs], \ʃ_ˈɪ_s_t_ə_ɹ_ˌa_s_ɪ_s]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.