SABUBRES GASTRIQUES
\sˈabʌbəz ɡastɹˈiːks], \sˈabʌbəz ɡastɹˈiːks], \s_ˈa_b_ʌ_b_ə_z ɡ_a_s_t_ɹ_ˈiː_k_s]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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