RECOMBINATION ACTIVATING GENE 1

\ɹˌiːkˌɒmbɪnˈe͡ɪʃən ˈaktɪvˌe͡ɪtɪŋ d͡ʒˈiːn wˈɒn], \ɹˌiːkˌɒmbɪnˈe‍ɪʃən ˈaktɪvˌe‍ɪtɪŋ d‍ʒˈiːn wˈɒn], \ɹ_ˌiː_k_ˌɒ_m_b_ɪ_n_ˈeɪ_ʃ_ə_n ˈa_k_t_ɪ_v_ˌeɪ_t_ɪ_ŋ dʒ_ˈiː_n w_ˈɒ_n]\

Definitions of RECOMBINATION ACTIVATING GENE 1

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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