POLYCHROITE

\pˌɒlɪkɹˈɔ͡ɪt], \pˌɒlɪkɹˈɔ‍ɪt], \p_ˌɒ_l_ɪ_k_ɹ_ˈɔɪ_t]\

Definitions of POLYCHROITE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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