OLYMPE AUDOUARD

\əlˈɪmp ˈɔːdwɑːɹəd], \əlˈɪmp ˈɔːdwɑːɹəd], \ə_l_ˈɪ_m_p ˈɔː_d_w_ɑː_ɹ_ə_d]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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