NUCLEOLITES

\njˈuːklɪˌɒla͡ɪts], \njˈuːklɪˌɒla‍ɪts], \n_j_ˈuː_k_l_ɪ__ˌɒ_l_aɪ_t_s]\

Definitions of NUCLEOLITES

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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